CONVERGENCE OF ENDOTHELIAL DYSFUNCTION, INFLAMMATION AND GLUCOCORTICOID RESISTANCE IN DEPRESSION-RELATED CARDIOVASCULAR DISEASES

Convergence of endothelial dysfunction, inflammation and glucocorticoid resistance in depression-related cardiovascular diseases

Abstract Major Depressive Disorder, or depression, has been extensively linked to dysregulated HPA axis function, chronic inflammation and cardiovascular diseases.While the former two have been studied in depth, the mechanistic connection between depression and cardiovascular disease is unclear.As major mediators of vascular homeostasis, vascular p

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An historical analysis of united states experiences using stamp-based revenues for wildlife conservation and habitat protection

Abstract In the United States, the transition from unchecked hunting, habitat loss, and species endangerment to an ongoing environmental awakening has been accutron legacy automatic examined through various lenses.Despite this gradual perspective shift, recent reports continue to warn of global declines in species and habitat diversity.As the need

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25-Hydroxycholesterol and 27-hydroxycholesterol inhibit human rotavirus infection by sequestering viral particles into late endosomes

A novel innate immune strategy, involving specific cholesterol oxidation products as effectors, has begun to reveal connections between cholesterol metabolism and immune response against viral shades eq 07m infections.Indeed, 25-hydroxycholesterol (25HC) and 27-hydroxycholesterol (27HC), physiologically produced by enzymatic oxidation of cholestero

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